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NBC's Ayman Mohyeldin answers your questions about Syria

Syria's defense minister and President Bashar Assad’s brother-in-law were killed in a Damascus bomb attack Wednesday, state TV reported. It appears to be the most serious blow to Assad’s regime in the country's 16-month-old rebellion. However no footage of the attack has emerged yet.

How significant is the attack? What does it mean for the future Assad regime? Or the Syrian military?

NBC News’ Ayman Mohyeldin answered reader questions about the significance of the attack earlier today. Click on the link below to replay the informative chat.

Bomb kills Syrian ministers at heart of Assad rule 


The defense minister, his deputy and a vice president were all killed in the blast but it is unclear if Syrian president Bashar al-Assad was nearby. NBC's Richard Engel reports.