A 65-year-old Frenchman is hospitalized after contracting France's first case of a deadly new respiratory virus related to SARS, and French health authorities said Wednesday they are trying to find anyone who might have been in contact with him to prevent it from spreading.

It's unclear how or where the man was infected with the novel coronavirus, which has killed 18 people and raised new public health concerns since being identified last year in the Middle East. It can cause acute pneumonia and kidney failure.

The patient fell ill after returning from a nine-day vacation in Dubai in the United Arab Emirates as part of a package tour, the Health Ministry said. Jean-Yves Grall, the French government health director, said the patient is in "worrying condition" under isolation and medical surveillance, receiving respiratory assistance and blood transfusions.

The man, whose identity was not released, returned from Dubai on April 17. He was hospitalized with respiratory problems in the northern French city of Valenciennes on April 23, and transferred to a more advanced facility in Douai on April 29, Grall told a news conference Wednesday.

Paris' Pasteur Institute analyzed the man's virus and confirmed Tuesday that it is a novel coronavirus.

Since September 2012, the World Health Organization has been informed of 30 confirmed cases of the virus, and 18 of the patients have died. Cases have emerged in Saudi Arabia, Jordan, the UAE, Qatar, Britain and Germany, and health officials say the virus has likely already spread from person to person in some circumstances.

Since the virus emerged last year, European authorities have put in place monitoring measures. In France, 20 people were examined for suspected cases of the virus, and the other 19 turned up negative, Health Minister Marisol Touraine said.

The patient who traveled to Dubai is the only positive case. His family members have been tested and are not infected, the Health Ministry said, and the other travelers in his tour group and health care workers who had contact with him are also being tested.

Authorities are trying to reach anyone else who was in contact with the patient before he was hospitalized, and a national hotline was established Wednesday for the public to call about the virus.

WHO has advised countries to test any people with unexplained pneumonia.

"Any virus that has the potential to develop into something that is highly transmissible between people, including the coronavirus, is a major concern," WHO spokesman Gregory Hartl said.

"We need to follow up on all possible routes of infection, i.e. animal to human, whether it's being spread in hospitals or from human-to-human," he said.

Health authorities are trying to determine how humans are contracting and spreading the virus and how best to treat it. It does not appear to be as contagious as SARS or the flu, but it seems to have spread among family members in Britain and in health workers in Jordan who were caring for patients, for example.

The new coronavirus is most closely related to a bat virus and scientists are considering whether bats or other animals like goats or camels are a possible source of infection.

Hartl said it's unclear whether there is something specific in the environment in the Middle Eastern countries where cases have been confirmed.

SARS, or severe acute respiratory syndrome, killed some 800 people in a 2003 epidemic.

Wang Zhao / AFP - Getty Images

A new strain of bird flu identified in China "is one of the most lethal influenza viruses we have seen so far," Dr. Keiji Fukuda, the World Health Organization (WHO)'s Assistant Director-General for Health Security, tells journalists at a press conference in Beijing on Wednesday.

BEIJING – A new type of bird flu that has killed 22 people in China since March is one of the most deadly strains of influenza known, international health experts said on Wednesday. 

"This is one of the most lethal influenza viruses we have seen so far," said Dr. Keiji Fukuda, the World Health Organization (WHO)’s Assistant Director-General for Health Security. "We are at the beginning of our understanding of this virus."

The H7N9 strain appears to spread more easily to humans than SARS, a different virus that started killing people in Asia a decade ago, experts said. Severe acute respiratory syndrome killed around 800 people globally in 2003 before it was stopped.

"This is an unusually dangerous virus for humans," added Fukuda, who was speaking in Beijing alongside leading flu experts from around the world.  

The delegation from United States, Europe, Hong Kong and Australia, as well as China, have just concluded a week-long investigation that took them to affected areas in Shanghai and Beijing.

Little is known
The group of experts made an impressive display of international cooperation, but at the same time admitted just how little is known about the virus that has infected 108 people since March.

"We are at the very early stages of this investigation," said Dr. Nancy Cox, who heads Influenza Division at the Center for Disease Control and Prevention in Atlanta. "There's a lot to be learned.”

Most of the cases so far have been found in eastern China, around the Yangtze River delta, but in recent days there have been cases in central and northern China, including the capital. Most have been what Fukuda called "sporadic cases."  

He said a few family clusters have been found, which could be the result of exposure to the same source of virus, or limited person-to-person transmission.

But he said: "'Evidence so far is not sufficient to conclude there is person-to-person transmission. Moreover, no sustained person-to-person transmission has been found.”

The experts concluded that live poultry markets were the most likely source of infection.

The experts praised the swift action of Chinese authorities in closing live poultry markets, and said it was "encouraging" that there have been no new cases in Shanghai since its markets were shuttered.

And they called for continued international cooperation against a virus that doesn't recognize borders. 

"The risks of an outbreak situation are shared in a globalized world, where we are all interconnected," said Fukuda.

Legacy of distrust
All of those who spoke today went out of their way to praise the response and of the Chinese authorities and their openness and transparency. There is enormous sensitivity to any suggestion that their presence in China implies any criticism of local efforts.

China still lives in the shadow of the SARS pandemic, which began here a decade ago and killed hundreds worldwide, including in the U.S. It was made worse by an initial cover-up by the Chinese authorities.

"The response reflects earlier and strong investments in health and preparedness made by China," said Fukuda.

SARS also left a legacy of distrust, which was on display earlier in the week in Shanghai, when a press conference by the local government and WHO was gatecrashed by the daughter of a couple infected with H7N9. The 26-year-old demanded information about her quarantined father; her mother had died.

"The hospitals and medical staff appear friendly to members of the media like you but have responded in a lukewarm manner to inquiries from family members like me," she told the South China Morning Post. She was taken away by officials.

The experts said that in the absence of so much basic information about the extent of the public health risk it was critical to maintain a high level of awareness. They also noted that the weather is warming up in China, which might provide a bit of a respite and buy them some important time, since H7N9 -- in common with other influenza -- spreads less easily in the spring and summer.

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This story was originally published on Wed Apr 24, 2013 6:19 AM EDT

Health Protection Agency via AP

A British Health Protection Agency photo shows an electron microscope image of a coronavirus, part of a family of viruses that cause ailments including the common cold and SARS. This one was first identified last year in the Middle East. A patient in Britain has died after being treated for the virus. So far 12 people have been diagnosed and six have perished.

LONDON -- A patient being treated for a mysterious SARS-like virus has died, a British hospital said Tuesday.

Queen Elizabeth Hospital in Birmingham, central England, said the coronavirus victim was also being treated for "a long-term, complex unrelated health problem" and already had a compromised immune system.

A total of 12 people worldwide have been diagnosed with the disease, six of whom have died.

The virus was first identified last year in the Middle East. Most of those infected had traveled to Qatar, Saudi Arabia, Jordan or Pakistan, but the person who just died is believed to have caught it from a relative in Britain, where there have been four confirmed cases.

The new coronavirus is part of a family of viruses that cause ailments including the common cold and SARS. In 2003, a global outbreak of SARS killed about 800 people worldwide.

Health experts still aren't sure exactly how humans are being infected. The new coronavirus is most closely related to a bat virus and scientists are considering whether bats or other animals like goats or camels are a possible source of infection.

Britain's Health Protection Agency has said while it appears the virus can spread from person to person, "the risk of infection in contacts in most circumstances is still considered to be low."

Officials at the World Health Organization said the new virus has probably already spread between humans in some instances. In Saudi Arabia last year, four members of the same family fell ill and two died. And in a cluster of about a dozen people in Jordan, the virus may have spread at a hospital's intensive care unit.

Related: 

New virus passed person-to-person in Britain, officials say

British officials say a mysterious virus related to SARS may have spread between humans, as they confirmed the 11th case worldwide of the new coronavirus in a patient who they say probably caught it from a family member.

The new virus was first identified last year in the Middle East and the 10 people who have previously been infected had all traveled to Qatar, Saudi Arabia, Jordan or Pakistan.

According to Britain's Health Protection Agency, the latest patient is a U.K. resident with no recent travel to any of those countries but who had close personal contact with an earlier case. The patient may also have been at greater risk of infection due to an underlying medical condition and is currently in intensive care at a Birmingham hospital.

"Although this case provides strong evidence for person to person transmission, the risk of infection in most circumstances is still considered to be very low," John Watson, head of the respiratory diseases department at the Health Protection Agency, said in a statement. "If (the) novel coronavirus were more infectious, we would have expected to have seen a larger number of cases."

Six hospital staffers where the patient is being treated are being monitored for infection but none has so far showed any symptoms of the illness. The patient did not come into contact with any other hospital patients and is currently being kept in isolation.

The new coronavirus is part of a family of viruses that cause ailments including the common cold and severe acute respiratory syndrome or SARS. In 2003, a global outbreak of SARS killed about 800 people.

Officials at the World Health Organization said the new virus has probably already spread between humans in some instances. In Saudi Arabia last year, four members of the same family became ill and two died. And in a cluster of about a dozen people in Jordan, the virus may have spread at a hospital's intensive care unit.

"We know that in some of those cases there was close physical contact between family members caring for one another, so we can't rule out human-to-human transmission," said Gregory Hartl, a WHO spokesman.

He said there were still big gaps in the understanding of the novel coronavirus, which can cause acute pneumonia and kidney failure. Of the 11 cases to date, five people have died.

Health experts still aren't sure how humans are being infected. The new coronavirus is most closely related to a bat virus and scientists are considering whether bats or other animals like goats or camels are a possible source of infection.

Michael Osterholm, an infectious diseases expert at the University of Minnesota, warned the virus could be adapting into a more transmissible form. "At any moment the fire hydrant of human-to-human transmission cases could open," he said. "This is definitely a 'stay tuned' moment." He said before SARS spread worldwide, there were a handful of human-to-human cases. Something such as a virus mutation may have triggered the explosion of cases.

WHO says the virus is probably more widespread than the Middle East and has advised countries to test any people with unexplained pneumonia.

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